Serendipitous discovery of Wolbachia genomes in multiple Drosophila species 英文参考文献.docVIP

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Serendipitous discovery of Wolbachia genomes in multiple Drosophila species 英文参考文献.doc

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Serendipitous discovery of Wolbachia genomes in multiple Drosophila species 英文参考文献

Open Access Re rch 2005SalzbergetVoal.lumesea6, Issue 3, Article R23 Serendipitous discovery of Wolbachia genomes in multiple Drosophila species Steven L Salzberg*, Julie C Dunning Hotopp*, Arthur L Delcher*, Mihai Pop*, Douglas R Smith?, Michael B Eisen? and William C Nelson* Addresses: *The Institute for Genomic Research, 9712 Medical Center Drive, Rockville, MD 20850, USA. ?Agencourt Bioscience Corporation, 100 Cumming Center, Beverley, MA 01915, USA. ?Center for Integrative Genomics, University of California, Berkeley, CA 94720, USA. Correspondence: Steven L Salzberg. E-mail: salzberg@ Published: 22 February 2005 Received: 22 December 2004 Revised: 24 January 2005 Accepted: 24 January 2005 Genome Biology 2005, 6:R23 The electronic version of this article is the complete one and can be found online at /2005/6/3/R23 ? 2005 Salzberg et al.; licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. WolbachiabiponBt yWsoelabragenomescchhiniagpthipeiinepnuDrosophilatbislicinlytahvraeieladsequencesbleifferepositoryrent specieofs oDNAf fruisequencingt fly: Drosoptracehila data,ananawessadiscoverede, D. simulthreeans, anewnd Dspecies. mojavofenthesis.bacterial/p endosym- Abstract Background: The Trace Archive is a repository for the raw, unanalyzed data generated by large- scale genome sequencing projects. The existence of this data offers scientists the possibility of discovering additional genomic sequences beyond those originally sequenced. In particular, if the source DNA for a sequencing project came from a species that was colonized by another organism, then the project may yield substantial amounts of genomic DNA, including near-complete genomes, from the symbiotic or parasitic organism. Results: By searching the