Substitution of exudative trace element losses in burned children 英文参考文献.docVIP

Stucki et al. Critical Care 2010, 14:439 /content/14/4/439 LET TER Substitution of exudative trace element losses in burned children Pascal Stucki , Marie-Hélène Perez , Jacques Cotting , Alan Shenkin and Mette M Berger * 1 1 1 2 3 We describe an intravenous copper-selenium-zinc Table 1. Composition of the antioxidant micronutrient substitution policy in children with major burns using solutions used in the adult ICU adult doses adapted to total body surface area. Blood levels and clinical course con? rm its safety, with a rapidly favourable clinical evolution. Intravenous CHUV-TE-? ex (250 ml) Enteral antioxidant glutamine solution (500 ml; Intestamine?) Micronutrient Copper (mg) Major burn injuries are associated with trace element de? ciencies, which lead to impaired wound healing and infectious complications. Low plasma levels of zinc (Zn) and copper (Cu) are inadequately compensated for during hospitalization [1], and enteral supplements are unsuccessful in correcting the status [2]. Additionally, there are currently no clear recommendations regarding 3.75 375 37.5 1,200 - - Selenium (μg) Zinc (mg) 300 30 - Phosphate (mg) Vitamin E (mg) Vitamin C (mg) Beta-carotene (mg) Glutamine (g) 500 150 10 30 - trace element requirements in childr e aim of the - present study was to determine if our trace element supplementation policy for adults adapted to total body - surface area would achieve normalization of plasma TE, trace elements: copper gluconate, sodium selenite solution, and zinc gluconate (Laboratoires Aguettant, Lyon, France), plus a multi-trace element preparation (Decan?, Aguettant). Intestamin?, Fresenius Kabi AG, Stans, co