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Towards defining the nuclear proteome 英文参考文献
Open Access
Re rch
2008FinketVoal.lumesea9, Issue 1, Article R15
Towards defining the nuclear proteome
¤
¤
J Lynn Fink *, Seetha Karunaratne ?, Amit Mittal?, Donald M Gardiner?,
Nicholas Hamilton?§, Donna Mahony?, Chikatoshi Kai?¥,
Harukazu Suzuki?¥, Yosihide Hayashizaki?¥ and Rohan D Teasdale*?
Addresses: *ARC Centre of Excellence in Bioinformatics, The University of Queensland, St Lucia, Queensland, 4072, Australia. ?Institute for
Molecular Bioscience, University of Queensland, St Lucia, Queensland, 4072, Australia. ?Department of Biochemical Engineering and
Biotechnology, Indian Institute of Technology, New Delhi, 110016, India. §Advanced Computational Modelling Centre, Department of
Mathematics, University of Queensland, St Lucia, Queensland, 4072, Australia. ?Genome Exploration Research, RIKEN Genomic Sciences
Center (GSC), RIKEN Yokohama Institute, 1-7-22 Suehiro-cho, Tsurumi-ku, Yokohama, Kanagawa, 230-0045, Japan. ¥Genome Science
Laboratory, Discovery Research Institute, RIKEN Wako Institute, 2-1 Hirosawa, Wako, Saitama, 351-0198, Japan.
¤ These authors contributed equally to this work.
Correspondence: Rohan D Teasdale. Email: R.Teasdale@.au
Published: 23 January 2008
Received: 15 August 2007
Revised: 19 December 2007
Accepted: 23 January 2008
Genome Biology 2008, 9:R15 (doi:10.1186/gb-2008-9-1-r15)
The electronic version of this article is the complete one and can be
found online at /2008/9/1/R15
? 2008 Fink et al.; licensee BioMed Central Ltd.
This is an open access article distributed under the terms of the Creative Commons Attribution License (/licenses/by/2.0), which
permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
NucleartepomDei.re/proteomectpevidence is reported for 2,568 mammalian proteins within the nuclear proteome, consisting of at least 14% of the entire pro-
Abstract
Background: The nucleus is a complex cellular organelle and accurately definin
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