Traits associated with innate and adaptive immunity in pigs heritability and associations with performance under different health status conditions 英文参考文献.docVIP

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Traits associated with innate and adaptive immunity in pigs heritability and associations with performance under different health status conditions 英文参考文献.doc

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Traits associated with innate and adaptive immunity in pigs heritability and associations with performance under different health status conditions 英文参考文献

Genetics Selection Evolution BioMedCentral Research Open Access Traits associated with innate and adaptive immunity in pigs: heritability and associations with performance under different health status conditions Mary Clapperton*1, Abigail B Diack2, Oswald Matika1, Elizabeth J Glass1, Christy D Gladney3, Martha A Mellencamp4, Annabelle Hoste5 and Stephen C Bishop1 Address: 1The Roslin Institute and Royal Dick School of Veterinary Studies, University of Edinburgh, Roslin, Midlothian, EH25 9PS, UK, 2Faculty of Veterinary Medicine, University of Glasgow, G61 IQH, UK, 3Genus, De Forest, WI 53532, USA, 4Ralco Nutrition, Inc., 1600 Hahn Road, Marshall, MN 56258, USA and 5JSR Genetics Ltd, Driffield, East Yorkshire, Y025 9ED, UK Email: Mary Clapperton* - Mary.Clapperton@roslin.ed.ac.uk; Abigail B Diack - abigail.diack@roslin.ed.ac.uk; Oswald Matika - Oswald.Matika@roslin.ed.ac.uk; Elizabeth J Glass - liz.glass@roslin.ed.ac.uk; Christy D Gladney - Christy.Gladney@; Martha A Mellencamp - marnie.mellencamp@; Annabelle Hoste - annabelle.hoste@; Stephen C Bishop - Stephen.Bishop@roslin.ed.ac.uk * Corresponding author Published: 30 December 2009 Received: 7 July 2009 Accepted: 30 December 2009 Genetics Selection Evolution 2009, 41:54 doi:10.1186/1297-9686-41-54 This article is available from: /content/41/1/54 ? 2009 Clapperton et al; licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. Abstract There is a need for genetic markers or biomarkers that can predict resistance towards a wide range of infectious diseases, especially within a health environment typical of commercial farms. Such markers also need to be heritable under these conditions and ideally correlate with commercial performance traits. In this study, we estimated