Transverse propagation of action potentials between parallel chains of cardiac muscle and smooth muscle cells in PSpice simulations 英文参考文献.docVIP

下载本文档

3
0
约5.35万字
约 17页
2017-05-16 发布于上海
举报
版权申诉

Transverse propagation of action potentials between parallel chains of cardiac muscle and smooth muscle cells in PSpice simulations 英文参考文献.doc

1、原创力文档（book118）网站文档一经付费（服务费），不意味着购买了该文档的版权，仅供个人/单位学习、研究之用，不得用于商业用途，未经授权，严禁复制、发行、汇编、翻译或者网络传播等，侵权必究。。
2、本站所有内容均由合作方或网友上传，本站不对文档的完整性、权威性及其观点立场正确性做任何保证或承诺！文档内容仅供研究参考，付费前请自行鉴别。如您付费，意味着您自己接受本站规则且自行承担风险，本站不退款、不进行额外附加服务；查看《如何避免下载的几个坑》。如果您已付费下载过本站文档，您可以点击这里二次下载。
3、如文档侵犯商业秘密、侵犯著作权、侵犯人身权等，请点击“版权申诉”（推荐），也可以打举报电话：400-050-0827(电话支持时间：9:00-18:30)。
4、该文档为VIP文档，如果想要下载，成为VIP会员后，下载免费。
5、成为VIP后，下载本文档将扣除1次下载权益。下载后，不支持退款、换文档。如有疑问请联系我们。
6、成为VIP后，您将拥有八大权益，权益包括：VIP文档下载权益、阅读免打扰、文档格式转换、高级专利检索、专属身份标志、高级客服、多端互通、版权登记。
7、VIP文档为合作方或网友上传，每下载1次，网站将根据用户上传文档的质量评分、类型等，对文档贡献者给予高额补贴、流量扶持。如果你也想贡献VIP文档。上传文档

Transverse propagation of action potentials between parallel chains of cardiac muscle and smooth muscle cells in PSpice simulations 英文参考文献

BioMedical Engineering OnLine BioMedCentral Research Open Access Transverse propagation of action potentials between parallel chains of cardiac muscle and smooth muscle cells in PSpice simulations Nicholas Sperelakis*1 and Bijoy Kalloor2 Address: 1Dept of Molecular Cellular Physiology, University of Cincinnati College of Medicine, Cincinnati, OH USA 45267-0576 and 2Dept of Electrical Engineering and Computer Sciences, University of Cincinnati College of Engineering, Cincinnati, OH USA 45221-0030 Email: Nicholas Sperelakis* - spereln@; Bijoy Kalloor - ksbijoy@ * Corresponding author Published: 03 March 2004 Received: 02 October 2003 Accepted: 03 March 2004 BioMedical Engineering OnLine 2004, 3:5 This article is available from: /content/3/1/5 ? 2004 Sperelakis and Kalloor; licensee BioMed Central Ltd. This is an Open Access article: verbatim copying and redistribution of this article are permit- ted in all media for any purpose, provided this notice is preserved along with the articles original URL. Transversetional cleftPropagationpotential in cardiac muscleTransverse Propagation in smooth musclePSpice simulationsElectric Field in junctional cleftJunc- Abstract Background: We previously examined transverse propagation of action potentials between 2 and 3 parallel chain of cardiac muscle cells (CMC) simulated using the PSpice program. The present study was done to examine transverse propagation between 5 parallel chains in an expanded model of CMC and smooth muscle cells (SMC). Methods: Excitation was transmitted from cell to cell along a strand of 5 cells not connected by low- resistance tunnels (gap-junction connexons). The entire surface membrane of each cell fired nearly simultaneously, and nearly all the propagation time was spent at the cell junctions, the junctional delay time being about 0.3 – 0.5 ms (CMC) or 0.8 – 1.6 ms (SMC). A negative cleft potential (Vjc) develops in the narrow junc