Treatment of bipolar disorder a complex treatment for a multi-faceted disorder 英文参考文献.docVIP

Annals of General Psychiatry BioMedCentral Review Open Access Treatment of bipolar disorder: a complex treatment for a multi-faceted disorder Konstantinos N Fountoulakis*1, Eduard Vieta2, Melina Siamouli1, Marc Valenti2, Stamatia Magiria1, Timucin Oral3, David Fresno2, Panteleimon Giannakopoulos4 and George S Kaprinis1 Address: 1Third Department of Psychiatry, Aristotle University of Thessaloniki, Greece, 2Bipolar Disorders Program, Hospital Clinic, University of Barcelona, IDIBAPS, Barcelona, Spain, 3Fifth Inpatient Department of Psychiatry and Outpatient Unit of Mood Disorders, Bakirk?y State Teaching and Research Hospital for Neuropsychiatry, Istanbul, Turkey and 4Department of Psychiatry, University of Geneva, Switzerland Email: Konstantinos N Fountoulakis* - kfount@med.auth.gr; Eduard Vieta - evieta@clinic.ub.es; Melina Siamouli - siamel@; Marc Valenti - evieta@clinic.ub.es; Stamatia Magiria - routsonis@; Timucin Oral - etoral@; David Fresno - evieta@clinic.ub.es; Panteleimon Giannakopoulos - Panteleimon.Giannakopoulos@medecine.unige.ch; George S Kaprinis - kaprinis@med.auth.gr * Corresponding author Published: 9 October 2007 Received: 5 April 2007 Accepted: 9 October 2007 Annals of General Psychiatry 2007, 6:27 doi:10.1186/1744-859X-6-27 This article is available from: /content/6/1/27 ? 2007 Fountoulakis et al; licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. Abstract Background: Manic-depression or bipolar disorder (BD) is a multi-faceted illness with an inevitably complex treatment. Methods: This article summarizes the current status of our knowledge and practice of its treatment. Results: It is widely accepted that lithium is moderately useful during all phases of bipolar illness and i