Two cases of occupational allergic contact dermatitis from a cycloaliphatic epoxy resin in a neat oil Case Report 英文参考文献.docVIP

Environmental Health: A Global Access Science Source BioMedCentral Case Report Open Access Two cases of occupational allergic contact dermatitis from a cycloaliphatic epoxy resin in a neat oil: Case Report Charlotte D Jensen* and Klaus E Andersen Address: Department of Dermatology, Odense University Hospital, University of Southern Denmark, Odense and National Allergy Research Centre, Gentofte, Denmark Email: Charlotte D Jensen* - charlotte.devantier.jensen@ouh.fyns-amt.dk; Klaus E Andersen - kea@dou.dk * Corresponding author Published: 26 March 2003 Received: 18 February 2003 Accepted: 26 March 2003 Environmental Health: A Global Access Science Source 2003, 2:3 This article is available from: /content/2/1/3 ? 2003 Jensen and Andersen; licensee BioMed Central Ltd. This is an Open Access article: verbatim copying and redistribution of this article are permitted in all media for any purpose, provided this notice is preserved along with the articles original URL. Abstract Background: Metal-working fluids contain complex mixtures of chemicals and metal workers constitute a potential risk group for the development of allergic contact dermatitis. Case presentation: Two metal workers developed allergic contact dermatitis on the hands and lower arms from exposure to a neat oil used in metal processing. Patch testing revealed that the relevant contact allergen was a cycloaliphatic epoxy resin, 1,2-cyclohexanedicarboxylic acid, bis(oxiranylmethyl) ester, added to the oil as a stabilizer. None of the patients had positive reactions to the bisphenol A-based epoxy resin in the standard series. Conclusions: These cases emphasize that well-known contact allergens may show up from unexpected sources of exposure. Further, it can be a long-lasting, laborious process to detect an occupational contact allergen and cooperation from the patient and the manufacturer of the sensitizing product is essential.