Two New Neolignans from Syringa velutina Kom. 英文参考文献.docVIP

Molecules 2009, 14, 953-958; doi:10.3390/moleculeOPEN ACCESS molecules ISSN 1420-3049 /journal/molecules Communication Two New Neolignans from Syringa velutina Kom. Xue-Song Feng 1,2,*, Yang Qu 2, Lei Xu 2, Da-Cheng Wang 3, Li-Jun Wu 2 , Fan-Hao Meng 1 and Ya-Ru Liu 1 1 School of Pharmaceutical Sciences, China Medical University, Shenyang, Liaoning, 110001, P. R. China; E-mails: fhmeng@ (F-H.H.), free1962514@ (Y-R.L.) 2 School of Traditional Chinese Medicines, Shenyang Pharmaceutical University, Shenyang, Liaoning, 110016, P. R. China; E-mail: quyang_7@ (Y.Q.), abcgdef6001@163.com (L.X.), wulijun_111@ (L-J.W.) 3 College of Animal Science and Veterinary Medicine, Jilin University, Changchun, Jilin, 130062, P. R. China; E-mail: wdc9928@ (D-C.W.) ? Author to whom correspondence should be addressed; E-mail: xsfeng@; Tel.: +86 Received: 8 January 2009; in revised form: 17 February 2009 / Accepted: 17 February 2009 / Published: 27 February 2009 Abstract: Two new neolignans, (7S,8R)-guaiacylglycerol-8-O-4′-sinapyl ether 9′-O-β-D- glucopyranoside (1) and (7S,8R)-syringylglycerol-8-O-4′-sinapyl ether 9′-O-β-D-gluco- pyranoside (2) were isolated from the leaves of Syringa velutina Kom.. Their structures were established by chemical properties and spectroscopic evidence. Keywords: Syringa velutina Kom.; Neolignans. Introduction Syringa (S.) velutina Kom. has been widely cultivated in the northern parts of China and Korea. Its leaves, flower buds, and bark have been used for many centuries in traditional Chinese medicine to treat infectious fevers, counteract in?amations, dampness and acute icteric hepatitis [1]. A previous phytochemical study on the genus Syringa led to the isolation of lignans, iridoid glucosides and so on [2]. For the purpose to finding more bioactive agents, a study on chemical constituents of S. velutina  Molecules 2009, 14 954 was carried out, and two new 8-O-4′ neolignans (compou