子宫腺肌病癌变并双侧卵巢转移临床病理观察.pdfVIP

• 190. JDiagPathol , March2016 , Vol. 23 , ~o. 3 doi: 10. 3969/j. issn.l∞7-8ω6.2016.03. ∞9 子宫腺肌病癌变并双侧卵巢转移临床病理观察 周晓秋，王东关，李红静，孙希印，王琳琳，李 青，李新功 (山东省立医院集团东营市人民医院病理科，山东东营 257091 ) [摘要] 目的探讨子宫腺肌病癌变并双侧卵巢转移病例的临床病理特点。方法 分析 1 例子宫腺肌病癌变并双 侧卵巢转移的组织学及免疫组化染色，并进行相关文献复习。结果 患者女性，44 岁。因子宫肌瘤5 年，下腹痛 20 余天入院。手术切除全子宫及双侧附件。巨检发现子宫肌层弥漫增厚并见多处灰黄色烂肉样组织溢出，子宫内膜较 光滑，局部呈息肉样。双侧卵巢均见灰白色肿物，与卵巢组织界限不清。大网膜见多处灰白色结节。镜下子宫肌层 见异位的子宫内膜腺体及间质，多处子宫内膜腺体呈重度不典型性并提润性生长，双侧卵巢均见多处癌灶，为子宫内 膜祥腺癌υ 输卵管外膜及大网膜均查见转移癌。结论本例子宫腺肌病和卵巢均发现子宫内膜样腺癌，但卵巢癌址 的生长分布不符合卵巢原发性子宫内膜样腺癌的特点，考虑卵巢的子宫内膜样腺癌灶来自子宫的转移。 [关键词] 子宫腺肌病; 恶变; 子宫内膜癌: 病理学 [中圄分类号] R737.33 [文献标识码] A [文章编号]1∞7 -8ω6(2016)03 -01佣-04 Malignant transformation of adenomyosis with metastasis to bilateral ovaries: a clinicopathological analysis ZHOU Xiao-qiu , WANG Dong-guan , LI Hong-jing , SUN Xi-yin , WANG Lin-lin , LI Qi吨， LI Xin-gong ( Department 01 Pathology , DongyÎ1可 Peoples Hospital , Shαndong Provencial Hospital Groups , Dongying 257091 , Chioo) Abstract: Purpose To explore the clinicopathological characteristics of the malignant transformation of adenomyosis with metastasis to bilateral ovaries. Methods One case of malignant transformation of adenomyosis with metastasis to bilateral ovaries was analyzed with the literature review. Immunohistochemical staining w出 performed. Results A 44- year-old woman was found to have myoma of uterus by ultrasound and had lower ahdominal pain for more than 20 days. Gross examination found that uterine muscular layer thickening and a few yellow rotten tissue overflowed; the endometrium was smooth and local polypoid. Gray white nodules were found in bilateral ovaries and omentum. The microscopic examination revealed endometroid glands and stroma were found in the myome