Virus Pathogen Database and Analysis Resource (ViPR) A Comprehensive Bioinformatics Database and Analysis Resource for the Coronavirus Research Community 英文参考文献.docVIP

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Virus Pathogen Database and Analysis Resource (ViPR) A Comprehensive Bioinformatics Database and Analysis Resource for the Coronavirus Research Community 英文参考文献.doc

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Virus Pathogen Database and Analysis Resource (ViPR) A Comprehensive Bioinformatics Database and Analysis Resource for the Coronavirus Research Community 英文参考文献

Viruses 2012, 4, 3209-3226; doi:10.3390/v4113209 OPEN ACCESS viruses ISSN 1999-4915 /journal/viruses Article Virus Pathogen Database and Analysis Resource (ViPR): A Comprehensive Bioinformatics Database and Analysis Resource for the Coronavirus Research Community Brett E. Pickett 1, Douglas S. Greer 1, Yun Zhang 1, Lucy Stewart 1, Liwei Zhou 2, Guangyu Sun 3, Zhiping Gu 2, Sanjeev Kumar 2, Sam Zaremba 2, Christopher N. Larsen 3, Wei Jen 2, Edward B. Klem 2 and Richard H. Scheuermann 1* 1 J. Craig Venter Institute, 10355 Science Center Dr., San Diego, CA 92121, USA; E-Mails: bpickett@ (B.E.P.); dgreer@ (D.S.G.); yun.zhang@ (Y.Z.); lstewart@ (L.S.) 2 Northrop Grumman Health Solutions, 2101 Gaither Rd., Rockville, MD 20850, USA; E-Mails: liwei.zhou@ (L.Z.); zhiping.gu@ (Z.G.); sanjeev.kumar@ (S.K.); sam.zaremba@ (S.Z.); wei.jen@ (W.J.); ed.klem@ (E.B.K.) 3 Vecna Technologies, 6404 Ivy Lane Suite 500, Greenbelt, MD 20770, USA; E-Mails: gsun@ (G.S.); clarsen@ (C.L.) * Author to whom correspondence should be addressed; E-Mail: rscheuermann@ (R.H.S.); Tel.: +1-858-200-1876; Fax: +1-858-200-1880. Received: 2 October 2012; in revised form: 13 November 2012 / Accepted: 14 November 2012 / Published: 19 November 2012 Abstract: Several viruses within the Coronaviridae family have been categorized as either emerging or re-emerging human pathogens, with Severe Acute Respiratory Syndrome Coronavirus (SARS-CoV) being the most well known. The NIAID-sponsored Virus Pathogen Database and Analysis Resource (ViPR, ) supports bioinformatics workflows for a broad range of human virus pathogens and other related viruses, including the entire Coronaviridae family. ViPR provides access to sequence records, gene and protein annotations, immune epitopes, 3D structures, host factor data, and other data types through an intuitive web-based search interface. Records returned from these queries can then be s