A randomised, double-blind, placebo-controlled trial of tropisetron in patients with schizophrenia.docVIP

Shiina et al. Annals of General Psychiatry 2010, 9:27 /content/9/1/27 PRIMARY RESEARCH Open Access A randomised, double-blind, placebo-controlled Primary research trial of tropisetron in patients with schizophrenia Akihiro Shiina1, Yukihiko Shirayama2, Tomihisa Niitsu3, Tasuku Hashimoto3, Taisuke Yoshida3, Tadashi Hasegawa1, Tadashi Haraguchi3, Nobuhisa Kanahara3, Tetsuya Shiraishi3, Mihisa Fujisaki1, Goro Fukami1, Michiko Nakazato1, Masaomi Iyo1,3 and Kenji Hashimoto*4 Abstract Background: Cognitive deficits in schizophrenia are associated with psychosocial deficits that are primarily