原创力文档Anabolic and catabolic responses of human articular chondrocytes to varying oxygen percentages.docVIP
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Anabolic and catabolic responses of human articular chondrocytes to varying oxygen percentages
Str?beletal.ArthritisResearchTherapy2010,12:R34
/content/12/2/R34
RESEARCH ARTICLE
OpenAccess
Anabolicandcatabolicresponsesofhuman
articularchondrocytestovaryingoxygen
percentages
SimonStr?bel1,MarkoLoparic1,2,DavidWendt1,AndreasDSchenk2,ChristianCandrian1,3,RaijaLPLindberg4,
FlorinaMoldovan5,AndreaBarbero1*,IvanMartin1
Abstract
Introduction:Oxygenisacriticalparameterproposedtomodulatethefunctionsofchondrocytesex-vivoaswell
asindamagedjoints.Thisarticleinvestigatestheeffectoflow(morephysiological)oxygenpercentageonthe
biosyntheticandcatabolicactivityofhumanarticularchondrocytes(HAC)atdiffer
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