Combination of pharmacotherapy and psychotherapy in the treatment of chronic depression A systematic review and meta-analysis.docVIP
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Combination of pharmacotherapy and psychotherapy in the treatment of chronic depression A systematic review and meta-analysis
Wolffetal.BMCPsychiatry2012,12:61
/1471-244X/12/61
RESEARCH ARTICLE
OpenAccess
Combinationofpharmacotherapyand
psychotherapyinthetreatmentofchronic
depression:Asystematicreviewand
meta-analysis
AlessavonWolff1*,LarsPH?lzel2,AnnikaWestphal1,MartinH?rter1andLeventeKriston1
Abstract
Background:Chronicdepressionrepresentsasubstantialportionofdepressivedisordersandisassociatedwith
severeconsequences.Thisreviewexaminedwhetherthecombinationofpharmacologicaltreatmentsand
psychotherapyisassociatedwithhighereffectivenessthanpharmacotherapyaloneviameta-analysis;andidentified
possibletreatmenteffectmodif
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