Combination of pharmacotherapy and psychotherapy in the treatment of chronic depression A systematic review and meta-analysis.docVIP

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Combination of pharmacotherapy and psychotherapy in the treatment of chronic depression A systematic review and meta-analysis.doc

Combination of pharmacotherapy and psychotherapy in the treatment of chronic depression A systematic review and meta-analysis

Wolffetal.BMCPsychiatry2012,12:61 /1471-244X/12/61 RESEARCH ARTICLE OpenAccess Combinationofpharmacotherapyand psychotherapyinthetreatmentofchronic depression:Asystematicreviewand meta-analysis AlessavonWolff1*,LarsPH?lzel2,AnnikaWestphal1,MartinH?rter1andLeventeKriston1 Abstract Background:Chronicdepressionrepresentsasubstantialportionofdepressivedisordersandisassociatedwith severeconsequences.Thisreviewexaminedwhetherthecombinationofpharmacologicaltreatmentsand psychotherapyisassociatedwithhighereffectivenessthanpharmacotherapyaloneviameta-analysis;andidentified possibletreatmenteffectmodif

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