Compatible solutes the key to Listerias success as a versatile gastrointestinal pathogen.docVIP

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Compatible solutes the key to Listerias success as a versatile gastrointestinal pathogen.doc

Compatible solutes the key to Listerias success as a versatile gastrointestinal pathogen

SleatorandHillGutPathogens2010,2:20 /content/2/1/20 LETTER TO THE EDITOR OpenAccess Compatiblesolutes:thekeytoListeria’ssuccess asaversatilegastrointestinalpathogen? RoyDSleator1,2*,ColinHill2 Abstract Recentlywereportedaroleforcompatiblesoluteuptakeinmediatingbiletoleranceandincreasedgastrointestinal persistenceinthefoodbornepathogenListeriamonocytogenes[1].Herein,wereviewtheevolutioninourunder- standingofhowtheselowmolecularweightmoleculescontributetogrowthandsurvivalofthepathogenboth insideandoutsidethebody,andhowthisstresssurvivalmechanismmayultimatelybeusedtotargetandkillthe pathogen.

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