Finding disease candidate genes by liquid association.docVIP

Open Access M d 2007LietVoal.lumeetho8, Issue 10, Article R205 Finding disease candidate genes by liquid association Ker-Chau Li*?, Aarno Palotie?§?￥, Shinsheng Yuan?, Denis Bronnikov§#, Daniel Chen§, Xuelian Wei*, Oi-Wa Choi§, Janna Saarela# and Leena Peltonen#** Addresses: *Department of Statistics, UCLA, 8125 Math Sciences Bldg, Los Angeles, California 90095-1554, USA. ?Institute of Statistical Science, Academia Sinica, Academia Road, Nankang, Taipei 115, Taiwan. ?The Finnish Genome Center and Department of Clinical Chemistry, University of Helsinki, Haartmaninkatu, 00290 Helsinki, Finland. §The Broad Institute of Harvard and MIT, Cambridge Center, Cambridge, Massachusetts 02142, USA. ?Department of Pathology and Laboratory Medicine, Gonda Researach Center, UCLA, Los Angeles, California 90095-1766, USA. ￥Department of Human Genetics, UCLA, 695 Charles E. Young Drive South, Los Angeles, California 90095-1766, USA. #National Public Health Institute, Helsinki, Finland, Biomedicum Helsinki, Haartmaninkatu, 00290 Helsinki, Finland. **Department of Medical Genetics, University of Helsinki, Biomedicum Helsinki, Haartmaninkatu, 00290 Helsinki, Finland. Correspondence: Ker-Chau Li. Email: kcli@. Leena Peltonen. Email: leena.peltonen@ktl.fi Published: 4 October 2007 Received: 16 April 2007 Revised: 23 August 2007 Accepted: 4 October 2007 Genome Biology 2007, 8:R205 (doi:10.1186/gb-2007-8-10-r205) The electronic version of this article is the complete one and can be found online at /2007/8/10/R205 ? 2007 Li et al; licensee BioMed Central Ltd. This is an open access article distributed under the terms of the Creative Commons Attribution License (/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. FindingsupscAepntiobcandidatevieliltaypcparnodaidiseasecdhateo gfienngenesdings.candidate/p genes by using gene-expression data has been developed and used to iden