125I放射性粒子在肝癌小病灶中的初步应用分析.pdfVIP

影像诊断与介入放射学2012 年第 21 卷第5 期 .379. ·介入放射学- 125 1 放射性粒子在肝癌小病灶中的初步应用分析 熊斌郑传胜梁惠民冯敢生王奇苏扬泼李浩 【摘要] 目的 探讨吁放射性粒子在肝癌小病灶中应用的安全性、可行性及初步效果。方法 11 例肝癌患 者肝内 15 处小病灶(直径3 cm)在 B 超或 CT 导向下经过穿刺途径植入『放射性粒子，术后 1-3d 行 SPECT 检 察评价粒子植入情况，CT 随访评价病灶治疗效果，随访 1-7 个月。结果 所有病灶均成功植入吁放射性粒子，1- 10 粒/病灶，共计 110 粒，患者未出现出血、感染、贫血等严重并发症;术后 1-3 d 行 SPECT 检查，证实『放射性粒 子均植入靶病灶，元体内移位，γ 射线覆盖病灶完全;1 个月后 CT 随访，靶病灶均明显变小。结论 肝癌小病灶在 125 超声或 CT 导向下经穿剌途径植入 1 放射性粒子安全可行，靶病灶明显变小;吨放射性粒子植入是治疗肝癌小 病灶的一种有效方法，可作为肝癌综合治疗方案中的一个选择。 125 【关键词} 肝癌; 1 粒子;γ 射线;超声 [doi: 1O.3969/issn.l005-8001却12.05.015] The preliminary application of 出1 seeds in the treatment of small hepatocellular cardnoma XIONG Bin , ZHENG Chuan-sheng , LlANG Hui-min , FENG Gan-shen , WANG Qi , SU Yang-bo , Ll hao. Department 01 Radiology , Xiehe Hospit a1, Tongji Medic a1 College , Huazhong University 01 Science and Technology , Wuhan 430022 , China Correspondi唔αuthor: ZHENG Chuan-巾晤， Email: 问zcsxh@sina. com [Abstract] Objective To investigate the security , feasibi1ity and primaηeffectiveness of 1251 seeds in the treatment of small hepatocellu1ar carcinoma. Methods In 11 patients , 1251 seeds were imp1anted in 15 1esions (3 cm) with the guidance of ultrasound or CT imaging. SPECT was performed 1-3 days after the irnp1antation and the patients were followed by from 1 to 7 months. Results A tota1 of 110 1挡1 seeds were successfully imp1anted in all 11 patients , 1-10 particles in each 1esion. There were no serious comp1ications such as b1eeding , infection , anemia after the produce r. It was demonstrated by