麝香保心丸论文麝香保心丸对胸痹气滞血瘀证患者中心动脉压的影响.docVIP

麝香保心丸论文：麝香保心丸对胸痹气滞血瘀证患者中心动脉压的影响 【中文摘要】通过测定胸痹气滞血瘀证患者含服麝香保心丸后中心动脉压值,然后进行统计分析,从客观上评价其对中心动脉压的影响,并与含服硝酸甘油片进行对比。为麝香保心丸在临床中的使用提供参考依据。方法：研究对象为2010年05月至2011年03月在江苏省中西医结合医院心脏科行冠脉造影术的患者,选取其中符合胸痹气滞血瘀证诊断标准的病例60例,随机分为两组,每组30例。分别给予舌下含服麝香保心丸或硝酸甘油片,观察患者含药后中心动脉压值变化。中心动脉压值是在冠脉造影术前,将指引导管送至主动脉根部,与有创压力测定仪器相连后直接测得,含服药物前和含服药物后1至5分钟期间每分钟测量并照相记录。运用统计学方法,比较测得数据,得出结论。结果：(1)麝香保心丸组含药后1min-5min内的主动脉根部血压与用药前相比无明显差异。含药后1min-5min血压与用药前血压比较,均见P0.05,无统计学差异。(2)硝酸甘油片组含药后主动脉根部血压与用药前相比有差异。含药后1-3mmin的收缩压、舒张压、平均动脉压与用药前比较,P0.05,无统计学差异；含药后4-5min的收缩压、舒张压、平均动脉压与用药前比较,P0.05,无统计学差异；含药后4-5mmin的收缩压、舒张压、平均动脉压与用药前比较,P0.05,有统计学差异。结论：麝香保心丸对胸痹气滞血瘀证患者的中心动脉压无明显影响；硝酸甘油片可影响中心动脉压。麝香保心丸与硝酸甘油片比较,具有明显差异性。临床应用时,对于心绞痛发作可能伴低血压的患者,选择麝香保心丸来缓解症状更为安全。 【英文摘要】:In order to evaluate the effect of SXBXW on the central arterial pressure mpersonality, we measured the central arterial pressure of the patient who was determined as Angina Pectoris of QI stagnation and blood stasis, analysis the data using SPSS, and compared it with Nitroglycerin piece in the same way。This study can offer the reference for Clinical rational drug use about SXBXW。Methods:The subjects of this study were the hospitalized patients who do coronary angiography in Jiangsu Provine on Integration of Chinese and Western Medicine between May 2010 and March 2011, and we selected 60 patients who were determined as QI stagnation and blood stasis, divided them into two groups randomly, and there were 30 cases each group。Respectively gave SXBXW or nitroglycerin pill to the two groups under the tongue, we observed the changes of blood pressure of aortic root, which were measured after the link of the guide catheter and pressure measuring instruments。We recorded the blood pressure data before gave the medicine and then took the 1 to 5 minutes period data dynamically after gave the medicine, meanwhile, we made photographic records。Then using SPSS we compared the data, draw conclusions。Results:(1) The blood pressure data in SXBXW group have no difference among before take the medici