注射用炎琥宁致严重不良反应1例.pdfVIP

208 • 病例报告 • June 2015, Vol.13, No.18 Guide of China Medicine 注射用炎琥宁致严重不良反应1例 胡明光 （广东省中山市坦洲医院药剂科，广东中山 528467 ） 摘要 【 】患者女性，46 岁，因急性上呼吸道感染于我院门诊治疗。给予注射用炎琥宁（400 mg qd）静脉滴注抗感染，静脉滴注 20 min 后， 患者出现头晕、呕吐胃内容物，立即停止输液、观察，随后患者症状加重，血压无法测量，立即给予肾上腺素注射液、地塞米松注射液、 多巴胺注射液、呋塞米注射液对症治疗，并给予吸氧处理，1 h 后症状改善，但又过了 1 h 患者出现全身抽搐，立即送本院重医学室进一 步治疗，当晚被诊断为心肌梗死，随后转上一级医院治疗。 关键词 【 】炎琥宁；不良反应；过敏性休克；心肌梗死 中图分类号：R969.3 文献标识码：B 文章编号：1671-8194（2015）18-0208-01 1 Cases of Adverse Reactions induced by Yanhuning Injection HU Ming-guang (Department of Pharmacy, Tanzhou Hospital of Zhongshan, Zhongshan 528467, China) [Abstract]  In 1 cases, 46 years old, female patients, because of the acute upper respiratory tract infection in the treatment of outpatients in our hospital. Given the succinate for injection (400mg QD) intravenous infusion of anti infection, intravenous drip of 20min, patients with dizziness, vomiting, stomach contents, immediately stop the transfusion, observe, then symptoms aggravated, blood pressure cannot be measured, immediately give Adrealine Injection, dexamethasone injection, dopamine injection, Furosemide Injection symptomatic treatment, and given oxygen processing, improve the symptoms of 1 hour, but also had 1 hour patients with convulsions, immediately sent to the hospital for further medical treatment room, that night was diagnosed as myocardial infarction, then to a level hospital treatment. [Key words]  Yanhuning; Adverse reaction; Allergic shock; Myocardial infarction 1 临床资料 有文献[2]报道，使用该溶媒稀释会使炎琥宁溶液的微粒数增加。当大微 患者女性，46岁，既往有青霉素过敏史。因急性上呼吸道感染于 粒进入人体的血管后，可引起过敏感或发热，甚至引起微血管栓塞。药