胃溃疡药物治疗(国外英文资料).docVIP

胃溃疡药物治疗 Drug treatment (1) H2 receptor antagonist: the main drug for treating ulcers, the treatment of DU is better. The treatment of drugs such as metformin (cimetidine), ranitidine, famotidine, etc. Simetidine is used in 200 mg, 3 times a day, and 400 mg before bed. Four weeks to heal at a rate of 70% ~ 70%, 8 weeks almost 100%, to 800 mg/d maintaining quantity, the recurrence rate of 44% a year, such as ulcer healing after dont amount to maintain to prevent recurrence, the recurrence rate more than 50% in a year. The common method of reitinidine is: 150mg, 2 times a day, and a maintenance dose of 150mg per night before bed. In four weeks, the healing rate of ulceration was 50% ~ 90%, 8weeks was 83% ~ 93%, and the application maintenance dose rate was about 35% a year. Phaotidine USES 20 mg, 2 times a day or 40 mg per night before bed. The curative effect is similar to that of rinitidine. (2) H + -k + atpase (proton pump inhibitor) : with omeprazole (g) as the representative, is the latest and strongest acid suppression effect of drugs, and mucosal protection and resistance to the effect of helicobacter pylori. Omeprazole in the treatment of peptic ulcer can not only relieve the symptoms of active rapidly accelerate ulcer healing, and in the long-term treatment with reliable maintain healing effect. About 64 per cent of patients who applied 20 to 60 mg of omeprazole daily were treated with symptoms and ulceration after 2 weeks of treatment. Compared with H2 receptor antagonists, omeprazole is more effective in relieving pain and more healing. (3) resistance to helicobacter pylori (Hp) treatment: for Hp have clear drugs inhibit or kill the main bismuth agent, metronidazole, or for indications, amoxicillin and clarithromycin, tetracycline, furazolidone, etc. Killing Hp increases the effectiveness and prevention of recurrence. However, there is no single drug that can effectively eradicate Hp, and the combination of the drugs is not high. About a lot of treatment, t