12听觉性语言刺激功能磁共振成像研究.pdfVIP

2003 22 6 # 461 # ü 中枢神经放射学þ 居胜红, 陈 峰, 郑凯尔, 季 倩, 杨天明, 滕皋军 = 目的 MR ( BOLD) (fMRI) 资料与方法 23 , 14 , 6 , 3 25 , BOLD 结果 fMRI -, 结 论 BOLD-fMRI BOLD-fMRI = Acoustic Language Test: A Functional MRI Study JU Shenghong, HEN Feng, ZHENG Kaier, et al. Department of Radiology, The Affiliated Zhongda Hospital, Medical School of Southeast University, Nanjing, Jiangsu Province 210009, P. R. hina = Abstract Obj ective To study the brain functional activation under the stimulation of acoustic language by using blood oxy- genation level dependent functional magnetic resonance imaging ( BOLD-fMRI) . Materials and Methods Twenty-three sub- jects, including 14 normal individuals, 6 cerebral neoplasms and 3 cerebral softening lesions, underwent acoustic language stimu- lus study. The functional imaging of brain cortex by BOLD technique was adopted. Results In all subjects, BOLD-fMRI showed regular signal intensity-time curve in local active areas. Distinct functional images were obtained in all cases. Displacement or shrinkage of functional activation area due to adjacent space-occupying lesions could be found. Conclusion BOLD-fMRI is an effective method in localizing acoustic language cortex and is valuable for evaluating intracranial mass lesion before surgery. = Key words Brain Language test MRI ( BOLD- , fMRI) , , , MRI 1 [ 1] 1991Belliveau 23, 16 , 7 , 8~ 72 , , BOLD-fMRI 32 14 [2~ 5] , , ,