下颌骨骨压缩动物实验的初步研究.pdfVIP

口腔正畸学 2005 年第 12 ~量第 1 期 • 27 • ·学苑， 下锁骨骨压缩动物实验的初步研究 黄晓峰曾祥龙 E摘要】 目的 初步探讨下倾骨体压缩的可能及压缩脑血远、组织学的改变。方法 使用铁合金骨 压缩器，植入 4 只北京本地犬右侧下顿骨体部。以 O. 5rrun/天和1. Orrun/3 天的频率缩短骨压缩楞，总共缩 短 5rrun; 在实验前、骨压缩究成眉 1 天、1 月和 3 月分别使用血液多普勒仪测量下顿颠动脉的血流量;在实 验前、骨压缩完成后 3 月分别观察下顿骨伏度的变化;观察压缩完成后 3 个月下颁骨的组织学变化。结果 L 下顿骨被缩短了，定位钉之间的距离平均减少了 4.5rrun; 实验犬有开牙含趋势。 2. 血液多普勒仪测量 发现，与实验前相比，同…时期对照侧减去实验侧血流量的数值在实验后 1 天下降了，以后逐渐升高至实 验前。 3. X 光片显示，实验前下顿骨体部压缩区中央密度减低;实验后动物的下顿骨比实验前缩短，压缩 区密度增商。 4. 组织学观察:压缩 3 月后的骨压缩区血管较为丰富，可以见到多核的破骨细胞，同时成骨 活跃。结论 使用压缩力可以将实验犬的下颁骨体缩短，下顿骨的血远在 3 个月内恢复正常，压缩区的骨 组织改建活跃。 E关键词】 骨压缩;下颁骨;动物模型;压缩 Mandibular osteocompression in a dog model Huang Xiaofeng , Zeng Xianglong De户αrtment of Orthodontics , Peking University School of Stomatology , Beijing 100081 [Abstract Objective To investigate the feasibility of osteocompress technique. and study the changes of blood flux and histology after mandible ost朋compress. Method The experiments were performed on four dogs. The titianium alloy osteocompressors were applied to shorten the right side of mandibule by O. 5 rrun per day for 10days and 1. Orrun every three days for 15days. X-ray , Doppler and histology examination were performed to investigate the bone and vessel change during osteocompressing. R剧uIt 1. The mandibule was compressed and open bit巳 tendency was exhibited. 2. The blood flux was decreased aft巴r osteocompressing irrunediately , hut it was almost incr巴as巳d to normal level after 3 months. 3. The X-ray films showed that the length