copd疾病简介与治疗-new-2003.pptVIP

* * * * * * * * * * * * 一项随机、双盲、交叉、安慰剂对照的研究中，共26例伴有夜喘症状的哮喘患者完成了此项研究，研究期间患者继续原有的药物治疗(包括口服/吸入激素和缓解药物)，并给予口服班布特罗片剂20mg或安慰剂治疗，每晚一次，持续14天，观察研究结束时受试者夜喘症状的变化。结果证实，帮备每晚一次，可有效改善各项夜间哮喘症状，包括咳嗽、喘息、呼吸困难、夜间觉醒和睡眠质量，与安慰剂之间存在统计学显著性差异。 Chloe 这是一项观察帮备改善哮喘患者夜喘症状方面疗效的研究。 患者在继续原有药物治疗（包括口服/吸入激素药物）的基础上，给予口服班布特罗片剂20mg或安慰剂治疗，每晚一次，持续14天，观察研究结束时受试者夜喘症状的变化。 帮备20mg每晚一次，可有效改善各项夜间哮喘症状，包括咳嗽，喘息、呼吸困难、夜间觉醒和睡眠质量，与安慰剂相比存在显著统计学差异。 对于伴随夜喘症状的哮喘患者，晚间加用帮备，可作为吸入激素抗炎治疗的必要辅助手段，明显提高患者生活质量。 * * 通过互动讨论，有利于加深对社区轻中度COPD诊治的理解 COPD是可以预防和治疗的，戒烟是最主要的预防措施 合理的综合治疗能提高患者生活质量，改善预后 双向转诊发挥所长，转得出接得住，更有益于COPD患者 * 属于病理变化 * * * * 本图说明吸烟与COPD发病的密切关系。吸烟者COPD的累积发病率高达35.5%，而不吸烟者仅为 7.8%，且吸烟者中不同程度的COPD发病率皆比不吸烟者的高。以上数据皆提示吸烟能增加COPD的发病。 Key Point Smoking is associated with a higher incidence of COPD. Those who quit smoking have a lower incidence of COPD. L?kke et al examined the risk of developing COPD in a general population over a period of 25 years and analyzed this risk in relation to different amounts of tobacco smoked. All individuals included in this study participated in the Copenhagen City Heart Study, which is a longitudinal study of several thousand individuals from the city of Copenhagen in Denmark. The data used were taken from the 4 examinations of the Copenhagen City Heart Study; 14,223 individuals went to the first examination, which was conducted from 1976 to 1978. Men and women (N=8045) aged 30 to 60 years with normal lung function who were nonasthmatics and who had adequate smoking data were chosen from this group and followed up for 25 years. Spiromety was checked at baseline and subsequently 3 additional spirometric examinations were done during the 25 years. This enabled the investigators to monitor for the development of COPD. Data on mortality came from the Danish Death Register. At the fourth examination, which was conducted between 2001 and 2003, all subjects reported whether they were current smokers, ex-smokers, or never smokers. Using this information, the investigators defined the following sub