颅内血管外膜细胞瘤颅外转移1例报告并文献复习.pdfVIP

• 36 • 中国综合临床2007 年 1 月第23 巷第 1 期 Clinical MedicÎnc of China ,January 2007 ,VoL71 ,No. 1 ·论著· 颅内血管外膜细胞瘤颅外转移 1 例报告 并文献复习 曹勇张愚植王军梅赵继宗张伟戴坷李光刘朝在 [摘要} 目的探讨颅内血管外膜细胞瘤和脑膜瘤颅外转移的危险因素和治疗lÆ.预后。方法 报道 我院2004 年收洁的 1 例颅内血管外膜细胞瘤颅外特秽，并检索 1987 年豆2004 年的国外文献，对发生颅外 转移的颅内血管外膜细胞瘤和脑膜瘤的病理类型、临床特征、治疗lÆ.预后进行临床分析。结果 肿瘤恶性程 度高、多次手术、不完全的手术切除、复友、侵及硬脑膜窦、肿瘤体积大，脑室内恶性肿瘤是在生颅外转移的危 险因素。颅外转移灶可行手术切除。发生转移多预后不良。结论. 对于具有友生颅外转移危险因素的颅内 血管外膜细胞瘤和脑膜瘤应注意排查转移灶;治疗中应避免可引起肿瘤通过血液和/或脑脊液转移的操作; 原发病业应尽量全切除，术后放疗;转移病业可行手术切除，也可放疗和/或化疗。 {关键词] 脑膜瘤; 血管外膜细胞瘤; 颅外转移; 放疗 【中图分类号] R 739.45 [文献标识码] A [文章编号] 1 ∞8-6315 (2007 )01 -0036-04 Ac皿e report and review of the literature on intracranial hemengiopericytomas metastasizing. Cα0 元r咳， Zhang Mω， zhi I Wang }unmei ,et al. Depαrtment 01 Neurosurgery ,Tiantan Hospital (Beijing 10∞50 ， China) [Abstract} Objective To discuss thc risk factors and prognosis conceming metastasizing hemangiopericyto- mas and meningioma. Methods One atient with metastases from hemangiopericytoma was reported and foreign and domestic literatures from 1987ω2∞4 were reviewed. 古le histopathological pattem and clinical features; treatment and prognosis of metastasizing hemangiopericytomas and meningiomas were anlayzed. Rcsults Hisωlogical malig- nancy ,incomplete tumor resection , recurrence ,vascular wall invasion and intraventrical malignant neuplasm were considered as the risk factors for the metastasizing of hemangiopericytom描 and meningiomas. 叽le metastasizing focus were removed if 阳sible. The prognosis of metastasizing hemangiopericytomas and meningioma w因 poor. Conclusion For patients with metastasizing hemangiopericytomas and meningioma having several above risk factors the metas- tasizing focus should be considered j during the surgery the manipulation which can lead to spreadin