Blackwell Publishing, Inc. C ○ 2005 International League Against Epilepsy Computerized Mot.pdf
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Blackwell Publishing, Inc. C ○ 2005 International League Against Epilepsy Computerized Mot
Epilepsia, 46(6):901–917, 2005
Blackwell Publishing, Inc.
C 2005 International League Against Epilepsy
Computerized Motion Analysis of Videotaped Neonatal Seizures
of Epileptic Origin
∗Nicolaos B. Karayiannis, ∗Guozhi Tao, ∗Yaohua Xiong, ∗Abdul Sami, ∗Bindu Varughese,
†James D. Frost, Jr., †‡Merrill S. Wise, and †‡Eli M. Mizrahi
∗Department of Electrical and Computer Engineering, University of Houston; †Peter Kellaway Section of Neurophysiology,
Department of Neurology; and ‡Department of Pediatrics, Baylor College of Medicine, Houston, Texas, U.S.A.
Summary: Purpose: The main objective of this research is the (80 cases). The outcome of the experiments verified that optical-
development of automated video processing and analysis proce- flow methods are promising computational tools for quantifying
dures aimed at the recognition and characterization of the types neonatal seizures from video recordings in the form of motion-
of neonatal seizures. The long-term goal of this research is the strength signals. The experimental results also verified that the
integration of these computational procedures into the develop- robust motion trackers developed in this study outperformed con-
ment of a stand-alone automated system that could be used as siderably the motion trackers based on predictive block matching
a supplement in the neonatal intensive care unit (NICU) to pro- in terms of both reliability and accuracy. The quantitative fea-
vide 24-h per day noninvasive monitoring of infants at risk for tures selected from motion-strength and motor-activity signals
seizures. constitute a satisfactory representation of neonatal seizures and
Methods: We developed and
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