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International Journal of Cardiology 142 (2010) 279 – 287
/locate/ijcard
Association between hyperuricemia and incident heart failure among older
adults: A propensity-matched study
O. James Ekundayo a , Louis J. DellItalia a,b , Paul W. Sanders a,b , Donna Arnett a ,
Inmaculada Aban a , Thomas E. Love c , Gerasimos Filippatos d , Stefan D. Anker e ,
Donald M. Lloyd-Jones f , George Bakris g , Marjan Mujib a , Ali Ahmed a,b,⁎
a University of Alabama at Birmingham, Birmingham, AL, United States
b VA Medical Center, Birmingham, AL, United States
c Case Western Reserve University, Cleveland, OH, United States
d University of Athens, Athens, Greece
e Charité Campus Virchow-Klinikum, Berlin, Germany
f Northwestern University, Chicago, IL, United States
g University of Chicago, Chicago, IL, United States
Received 7 January 2009; accepted 7 January 2009
Available online 6 February 2009
Abstract
Background: The association between hyperuricemia and incident heart failure (HF) is relatively unknown.
Methods: Of the 5461 community-dwelling older adults, ≥ 65 years, in the Cardiovascular Health Study without HF at baseline, 1505 had
hyperuricemia (baseline serum uric acid ≥ 6 mg/dL for women and ≥ 7 mg/dL for men).
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