健康男性前列腺健康指数各年龄段分布曲线特征和临床意义.pdf

3836 ()2014 11 8 21 Chin J Clinicians(Electronic Edition),November 1,2014,Vol.8,No.21  PSA PHI 2381090 tPSAfPSAp2PSA10895%CI tPSAfPSA%fPSAp2PSA%p2PSAPHI PHIPHI10 29 2 130 39 PHI 31.8310.2995% CI 10.2953.376069PHI 42.859.0695% CI 23.96 61.754049PHI 9.162.05 95% CI 8.1916.76fPSA PHItPSAPHI6069tPSA10 PHIPSA PHIPSA  An initial study on male age-related distribution curves characteristics of prostate health index in a * health survey report Sun Weigui , Xia Huixin, Zheng Qichuan, Li Zhizhen, Wu Ping, Hu Xiaowu, Liang * Chaozhao. Department of Urology, Maanshan Peoples Hospital, Maanshan 243000, China Corresponding author: Sun Weigui, Email: docswg@ Abstract Objective To study some potential values of prostate health index (PHI) contrasted to conventional PSA tumor markers in health men. Methods 238 healthy men, aged from 10 to 90, were whole-randomly classified with every 10-year-old into 8 groups. tPSA, fPSA,%fPSA,p2PSA,%p2PSA and PHI levels in their sera were individually detected or calculated at same time, including the mean levels and the 95% confidence intervals (CI) of each group. All data were analyzed by SPSS 19.0 statistics software, and their each age-related distribution curves were also comparatively studied. Results Compared to the other indexes, PHI curve had some apparently discriminate characteristics in male lifetime as follows. After a slightly flat curve in 10-29 age areas, however, 2 mountain-peaks and 1 low-valley were subsequently arrived: the 1st peak located in 30-39 age points with PHI=31.83±10.29 (95% CI 10.29-53.37); the 2nd peak showed in 60-69 age regions as PHI=42.85±9.06 (95% CI 23.96-61.75); the unexpected valley appeared in 40-49 age ranges by PHI=9.16±2.05 (95% CI 8.19-16.76). Moreover, after 60-69 years old, deviated from fPSA, PHI bega