p7-2 Eur Heart J,2006,27：2667—2674.pdf

European Heart Journal (2006) 27, 2667–2674 Clinical research doi:10.1093/eurheartj/ehl334 Coronary heart disease A systematic review and meta-analysis on the hazards of discontinuing or not adhering to aspirin among 50 279 patients at risk for coronary artery disease 1* 2 3 4 Giuseppe G.L. Biondi-Zoccai , Marzia Lotrionte , Pierfrancesco Agostoni , Antonio Abbate , 5 2 1 1 6 Massimiliano Fusaro , Francesco Burzotta , Luca Testa , Imad Sheiban , and Giuseppe Sangiorgi 1 Interventional Cardiology, Division of Cardiology, University of Turin, corso Bramante 88-90, 10126 Turin, Italy; 2 Institute of Cardiology, Catholic University, Rome, Italy; 3 Antwerp Cardiovascular Institute Middelheim, AZ Middelheim, Antwerp, Belgium; 4 Department of Medicine, Medical College of Virginia Campus, Virginia Commonwealth University, Richmond, VA, USA; 5 Hemodynamics and Cardiovascular Interventions Service, Abano Terme Hospital, Abano Terme, Italy; and 6 EMO Centro Cuore Columbus, Milan, Italy Received 21 September 2006; accepted 5 October 2006; online publish-ahead-of-print 19 October 2006 KEYWORDS Aims The role of aspirin in patients with coronary artery disease (CAD) is well established, yet patients Aspirin; happen to discontinue aspirin according to physician’s advice or unsupervised. We thus undertook a Coronary artery disease; systematic review to appraise the hazards in