根除幽门螺旋杆菌及不同亚型老年功能性消化不良疗效关系.docVIP

根除幽门螺旋杆菌及不同亚型老年功能性消化不良疗效关系 　　[摘 要] 目的：分析根除幽门螺旋杆菌（Helicobacter pylori，HP）与不同亚型老年功能性消化不良（Functional dyspepsia，FD）??效的关系。方法：2013年6月―2015年6月收治184例HP阳性老年FD患者，按照随机数字表法分为抗HP组、常规组各92例。均予FD常规治疗，抗HP组加用HP根除治疗，观察抗HP组HP根除成功情况，比较不同亚型患者治疗1个月后、治疗1年后疗效及复发情况。结果：抗HP组治疗1个月后、治疗1年后FD治疗总有效率分别为78.26%、72.83%，均高于常规组的59.78%、57.61%；HP根除成功组治疗1个月后、治疗1年后总有效率分别为95.24%、98.21%，均高于HP根除失败组的68.42%、46.15%；抗HP组EPS亚型患者治疗1个月后、治疗1年后总有效率分别为86.00%、80.00%，均高于PDS亚型的69.05%、64.29%，差异有统计学意义（P0.05）。结论：根除HP可提高EPS型老年PD患者临床疗效 [关键词] 幽门螺旋杆菌；老年；功能性消化不良；疗效 中图分类号：R573.6 文献标识码：A 文章编号：2095-5200（2017）01-077-03 DOI：10.11876/mimt201701031 Relationship between eradication of Helicobacter pylori and different subtypes of functional dyspepsia in elderly patients ZHANG Yue，ZHONG Yuan. （Department of Geriatrics，Shanghai No.6 Peoples Hospital，Shanghai 200233 China） [Abstract] Objective： This study objective was to analyze the relationship between eradication of Helicobacter pylori （HP） and different subtypes of functional dyspepsia （FD） in elderly patients. Methods： 184 elderly HP-positive FD patients admitted in our hospital from June 2013 to June 2015， were divided into anti-HP group and routine group （n=92） by the random number table. All patients were given conventional treatment of FD， anti-HP group was treated with HP eradication， and the eradication of HP in anti-HP group was observed， and the curative effect and recurrence of patients with different subtypes were compared between 1 month after treatment and 1 year after treatment. Results： The total effective rate of FD1 month after treatment and 1 year after treatment were 78.26% and 72.83%， respectively， which were both higher than59.78% and 57.61% in the routine group； the total effective rate of the anti-HP group 1 month after treatment and 1 year after treatment were 95.24% and 98.21%， respectively， were both higher than 68.42% and 46.15% of the routine group； the total effective rate of subtype of EPS patients in anti-HP group1 months after treatment and 1