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脂联素在皖南花猪免疫器官表达的发育规律及对免疫的影响论文
showed no developmental change in general. Serum IgG, IgA and IgM was higher in
Wannanhua gilts than those in Wannanhua boars(P 0.05 or P 0.01).
2 Developmental patterns ofAdp, AdpR mRNA and immune related genes expressions in
Wannanhua pigs and their tissue specificity and sexual dimorphism.
(1) Adp mRNA expression in SP changed with age significantly(P0.05), which were
significantly lower in SP than those in CLN (P 0.05); AdpR1 and AdpR2 mRNA expression
in SP and CLN were changed with age significantly(P0.01), and AdpR2 mRNA expression
were significantlyhigher in CLN than those in SP(P 0.05).
(2) TNFα mRNA expression in CLN and SC adipose tissue changed with age
significantly(P 0.05 or P 0.01), which were significantly higher in SP than those in CLN
(P 0.05) before ablactation, but then opposite after weaning. TNFα mRNA expression in
SC adipose tissue was significantly higher than that in PR adipose tissue in general;
IL6 mRNA expression in SP, CLN, SC adipose tissue and PR adipose tissue all changed
with age significantly(P 0.05 or P 0.01), which were significantly higher in SP than those
in CLN(P 0.05).
(3) Although the sexual dimorphism were found in apart genes or apart days of age,
Adp、AdpR1、AdpR2、 TNFα and IL6mRNA expression both in SP and CLN had no
significant differences betweenWannanhua gilts and boars in general. TNFα and IL6mRNA
expression in SC adipose tissue and PR adipose tissue had the same situation.
(4) Significant positive correlation was found betweenAdp and AdipoR1 in SP (r = 0.39,
P0.05), and significant positive correlation were found between TNFα and IL6 in SP、
CLN and SC adipose tissue(r = 0.54,P0.01; r = 0.70,P0.01; r = 0.64, P0.01).
The results suggested that blood biochemical parameters of Wannanhua pigs show special
developmental patterns and sexual dimorphism to some extent. Adp、A dpR1、A dpR2、T NFα
and IL6 may
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