不同年龄与性别之间高血压病患者血脂特点论文.docVIP

　　不同年龄与性别之间高血压病患者血脂特点论文 王应鹏，王归真，殷彩桥，杨燕，徐凤九，席芳娴 【关键词】 高血压；血脂；年龄；性别 【Abstract】 AIM: To analyze the characteristics of blood fat of hypertensive patients in different age periods and of different sexes and to provide reference for the prevention and treatment of high blood pressure. METHODS: Hypertensive patients (n=629) ale group and female group, and blood fat levels ales and females.RESULTS: ① The levels of cholesterol (TC) and loong females than males in each group. The male patients blood fat peak level appeared in Group B (51-60 years) and the female patients appeared in Group C (61-70 years). ② The levels of triglyceride (TG) and apolipoprotein B (apo B) ong males than females in Group A (≤50 years) and B (50-60 years), but ong females than males in Group C (61-70 years), D (71-80 years) and E (≥81 years). The male patients blood fat peak level also appeared in Group B（51-60 years）and the female patients appeared in Group C（61-70 years). ③ The levels of highdensity lipoprotein cholesterol（HDLC） and apolipoprotein A （apo A） changed little. Group C（61-70 years） had the male patients loale patients blood fat peak level. The blood fat level ong females than males in each group. ④ ale group，the blood fat level ong females than males.CONCLUSION: The blood fat level of hypertensive patients shoong females than males. The peak level of males appears betales appears betong females than males. 【KeymHg(1 mmHg=0.1333 kPa) 147例；高血压1级(140～159/90～99 mmHg) 213例；2级(160～179/100～109 mmHg) 175例, 3级( 180/110 mmHg) 94例. 同时患有冠心病345例，糖尿病85例;有高血压遗传史者87例. 1.2方法所有患者于入院时平卧位测量2次血压，以Korotkoff第1音为收缩压，第4音为舒张压(无第4音时则以第5音为准). 于次日清晨抽取空服静脉血，TC，TG试剂盒及标准品由上海长征医学科学有限公司提供，HDLC一步方法试剂盒由卫生部上海生物制品研究所提供. 实验室分离血清备用，随机带室内质控(日本第一化学质控品). TC，TG，HDLC用酶法测定(单位：mmol/L). 低密度脂蛋白胆固醇(LDLC)用Friedwalds公式换算，即LDLC=TC－HDLC－TG/2.2，为消除TG值在 4.52时造成LDLC的偏差，所有乳糜血清样本结果未纳入本文统计. 载脂蛋白(apo A)和载脂蛋白B(apo B)用免疫透射比浊法测定，试剂盒由上海科华生物工程股份有限公司提供. 所有患者按年龄大小分为5组：A组61例，≤50岁；B组82例，51～60岁；C组221例，61～70岁；D组214例，71～80岁；E组51例，≥81岁. 每组按性别分为男和女，A组分别为