肾功能检查-培训课件.pptVIP

Tests of tubular function肾小管功能检查 Tests of proximal tubular function近端肾小管功能检测 Urine β2-microglobulin, β2-MG Freely filtrated by glomeruli Almost reabsorbed by tubules completely Threshold of reabsorption:5mg/L Normal value: Urine：0.3mg/L Clinical Significance GFR： Serum β2-MG ↑:more sensitive than Scr when Ccr80ml/min Reabsorption function of proximal tubules： bloodβ2-MG5mg/L,urineβ2-MG increase Acute and chronic pyelonephritis Clinical Significance Evaluation for transplant kidney function urineβ2-MG↑↑，implied graft rejeciton 排异时血β2-MG增高先于Ccr，测定β2-MG有助于诊断尚处于亚临床期的肾排异反