信必可联合复方甲氧那明治疗支气管哮喘疗效及肺功能变化临床分析.docVIP

信必可联合复方甲氧那明治疗支气管哮喘疗效及肺功能变化临床分析 　　【摘要】 目的：探讨信必可联合复方甲氧那明治疗支气管哮喘的效果及肺功能变化的临床分析。方法：回顾性分析2014年8月-2016年3月在本院呼吸科支气管哮喘急性发作的60例住院患者的临床资料，按照给药方式不同分为复方组和单一组，各30例。单一组遵医嘱给予信必可治疗，复方组在单一组的基础上遵医嘱给予复方甲氧那明胶囊治疗，治疗周期均为4周。观察记录两组患者治疗前后的临床症状、肺功能及血清炎性因子IL-6、TNF-α水平。结果：治疗4周后，复方组咳嗽有效率明显高于单一组，差异有统计学意义（P0.05）。治疗4周后，两组患者的FEV1、PEFR、FEV1/FVC均较治疗前有明显改善，差异均有统计学意义（P0.05）。结论：应用信必可联合复方甲氧那明治疗支气管哮喘，可明显改善患者临床症状、肺功能水平，降低血液炎性因子水平，效果?@著，且不良反应轻微，安全度较高，值得临床推广应用 【关键词】 信必可； 复方甲氧那明； 疗效； 肺功能 Clinical Analysis of Curative Effect of Symbicort Turbuhaler Combined with Compound Methoxyphenamine in Treatment of Patients with Bronchial Asthma and Lung Function Changes/LUO Chao-feng，HUANG Bao-qiang.//Medical Innovation of China，2017，14（09）：112-115 【Abstract】 Objective：To explore the clinical analysis and efficacy of Symbicort Turbuhaler and Compound Methoxyphenamine in treatment of bronchial asthma and pulmonary function changes.Method：60 bronchial asthma patients were retrospectively analyzed from August 2014 to March 2016 from in our hospital，according to the dosing methods，all patients were divided into compound group and single group，30 cases in each group.The single group was given Symbicort Turbuhaler，on the basis of single group，the compound group was given Compound Methoxyphenamine Capsule，the treatment period was 4 weeks.The clinical symptoms，pulmonary function，serum inflammatory factors IL-6 and TNF-α levels were observed and recorded before and after treatment between the two groups.Result：After 4 weeks of treatment，the effective rate of cough in compound group was significantly higher than that of single group，the difference was statistically significant（P0.05）.After 4 weeks of treatment，the FEV1，PEFR and FEV1/FVC of the patients in the two groups were significantly improved compared with those before treatment，the differences were statistically significant（P0.05）.Conclusion：The application Symbicort Turbuhaler combined with Compound Methoxyphenamine treatment of bronchial asthma，can significantly im