胆汁淤积性肝病的发生机制及治疗进展-培训课件.pptVIP

Pruritus was scored by a semiquantitative scale of 1–4, with grade 1 ?occasional pruritus, grade 2 ?daily intermittent pruritus with preponderance of asymptomatic periods, grade 3 ?daily intermittent pruritus with preponderance of symptomatic periods and grade 4 ?persistent pruritus, day and night. * * * * study was to evaluate the efficacy and safety of ursodeoxycholic acid in comparison with cholestyramine. Eighty-four symptomatic patients with intrahepatic cholestasis of pregnancy were randomized to receive either ursodeoxycholic acid, 8-10 mg/kg body weight daily (n = 42), or cholestyram