第六章片剂儿科中成药的红外指纹图谱研究.PDFVIP

Scientific Journal of Frontier Chemical Development SJFCD 三种儿科中成药的红外指纹图谱研究 1 1 1 1 1 2* 杨莉丽 ，秦旭华 ，罗永静 ，姜金枝 ，凌芝 ，张德强 1.河北师范大学化学与材料科学学院，河北石家庄 050016 2.河北省科学院，河北石家庄 050081 摘 要：对小儿鼻炎片、小儿清肺止咳片和小儿清感灵片的红外图谱进行了研究，分别采用聚类分析法对 3 种中成药红外 图谱进行了考察，采用平均值法建立3 种中成药的红外指纹图谱，采用特征曲线重合率来表示图谱间的相似程度，结果表明 三种中成药的红外指纹图谱存在显著差别，可以用于三种中药的定性鉴别。 关键词：小儿鼻炎片；小儿清肺止咳片；小儿清感灵片；聚类分析法；红外指纹图谱；特征曲线重合率 Study on the Infrared Fingerprints of Three Kinds of Chinese Patent Medicines for Children 1 1 1 1 1 2* Lili Yang , Xuhua Qin , Yongjing Luo ,Jinzhi Jiang , Zhi Ling , Deqiang Zhang 1.College of Chemistry and Materials Science, Hebei Normal University, Shijiazhuang Hebei, China, 050016 2. Hebei Academy of Sciences,Shijiazhuang Hebei, China, 050081 Abstract: The consistency of the infrared spectrograms of thirty samples of each kind of Chinese Patent Medicines for Children was investigated by cluster analysis. The results show that the infrared spectrograms of thirty samples of Xiao’er Biyan Pian , Xiao’er Qingfeizhike Pian and Xiao’er Qingganling Pian were in good agreement, respectively. The infrared fingerprints of three kinds of Chinese Patent Medicines were established by average method. The infrared fingerprints of three kinds of Chinese Patent Medicines were compared using the similarity degrees of the characteristic curves. The results indicate that the significant difference was observed between two kinds of Chinese Patent Medicines and the infrared fingerprint