静脉血栓栓塞的诊疗选择--培训课件.pptVIP

Lee C-H, et al. J Thromb Haemost 2010; 8: 1515–23 临床复发率：亚洲数据5个月抗凝治疗后，VTE复发率仍高 该研究纳入台湾国民健康保险数据库5347例于2001-2002年期间诊断为VTE的患者，平均抗凝5.2个月，统计VTE自然病程的发病率和复发率 The crude incidence of VTE was 15.9 per 100 000 person-years, and its recurrence rate was 5.1% per person-year. During 11 566 person-years of follow-up, the cumulative rates of VTE recurrence at 6, 12, 24, 36 and 47 months were 6.7%, 9.4%, 12.4%, 13.9%, and 14.4%, respectively. Hutten B, Prins M. Cochrane Database Syst Rev 2006;1:CD001367 荟萃分析：长期抗凝较短期抗凝显著降低VTE复发风险 长期抗凝较短期抗凝显著降低VTE复发风险达82% (OR=0.18, 95%CI 0.13-0.26) 荟萃分析，纳入8项随机对照研究，2,994例患者，旨在比较