多杀菌索产生菌的5L罐分批发酵动力学研究.PDFVIP

2011NO．7 China ·78· SerialNo．232 Brewing Research Report 多杀菌素产生茵的5L罐分批发酵动力学研究 王燕，万红贵·，袁建峰，蔡恒 (南京工业大学生物与制药工程学院，江苏南京210009) 7．5软件对实验值与模型拟合值进行比较，两者能较好的吻合．说明所建动力学模型能较好反映多杀菌素的分 数学模型。并用origin 批发酵过程，为工业放大生产多杀菌素提供了理论依据和方法。 关键词：多杀菌素：发酵动力学；模型 中图分类号：TQ920．1 文献标识码：A 文章编号：0254-5071(2011)07—007蛐3 Batchfermentationkinetics strainina5-Lfermentor ofspinosad producing WANG Yan,WAN Honggui‘，YUANJianfeng,CAIHeng ofBiotcchnologyandPharmaceuticalEngineering,Nanfing (College isa microbial the ofboth of andfasteffectof insecticide，whichpropertiessafetybiologicalpesticide agro- AbsUac；t=Spinosadnew-style posscs8es chemical．Thebatchfermentationkineticsof suainina 5-Lfermentorwasstudied．Mathematicmodcbof spinosad myocliagrowth, producing andsubstrate wereestablishedoilthebasisofthe values spinosadproduction consumption Logis啦andLuedeking-Piret software arc kineticmodelscouldwelldescribethe fittedvaluesmodelswith 7．5and wellcoincident．The wele∞蜘pared by origin they proposed theoreticalbaseandmethodsfor of ofbatchfermentationof the processing processspinosadproduction，andtheyprovided large-scalespinosad production． Keywords：spinosad；fermentationkinetic