过敏性鼻炎的辨证施治及现代研究.pptx

過敏性鼻炎的辨證施治及現代研究;过敏性鼻炎指南及诊疗标准 ; ARIA program First phase: Development of evidence-based guidelines during a workshop held at WHO in December 1999 (J Allergy Clin Immunol, suppl, Nov 2001). Document has been endorsed by several allergy, respiratory, ENT and pediatric associations. Second phase: To produce materials to help improve delivery of care to those with rhinitis. In particular a pocket guide To implement ARIA guidelines To update the workshop report ; The ARIA initiative was developed as a state-of-the-art for the specialist, the general practitioner and for health care workers: to update their knowledge of allergic rhinitis, to highlight the impact of allergic rhinitis on asthma, to provide an evidence-based documented revision on the diagnosis methods, to provide an evidence-based revision on the treatments available, to propose a stepwise approach to the management of the disease, to assess the magnitude of the problem in developing countries and to implement guidelines;Allergic rhinitis is a major chronic respiratory disease Allergic rhinitis is associated with sinusitis and other co-morbidities such as conjunctivitis Allergic rhinitis should be considered as a risk factor for asthma A new subdivision of allergic rhinitis has been proposed: Intermittent (IAR) Persistent (PER) The severity of allergic rhinitis has been classified as mild and moderate/severe“ A stepwise therapeutic approach has been proposed The treatment of allergic rhinitis combines: Allergen avoidance (when possible) Pharmacotherapy Immunotherapy Education Patients with persistent allergic rhinitis should be evaluated for asthma (10-40%) Patients with asthma should be appropriately evaluated for rhinitis.(over 80%) A combined strategy should be ideally used to treat the upper and lower airway diseases in terms of efficacy and safety.;变态反应、特应性、过敏性鼻炎的概念;变应性鼻炎的流行病学;病因;变应性鼻炎发病有两个阶段： 致敏阶段：当鼻黏膜接触到抗原（如花粉、霉菌、室尘等）后，经巨噬细胞吞噬处理，将抗原信息传递给免疫活性Ｔ、Ｂ淋巴细胞，在Ｔ淋巴细胞的辅助下，Ｂ淋巴细胞分裂增殖，转变为产生抗体的浆细胞