氟尿苷二乙酸酯脂质固体纳米粒的制备论文.docVIP

　　氟尿苷二乙酸酯脂质固体纳米粒的制备论文 连佳芳，张三奇，顾宜，石小鹏，奚苗苗 【关键词】 固体 Preparation of floxuridine diacetate solid lipid nanoparticles 【Abstract】 AIM: To prepare floxuridine diacetate solid lipid nanoparticles (FUDRASLN) so as to improve the treatment efficacy and reduce the side effects of floxuridine (FUDR). METHODS: FUDR ethylaminopyridine. The structure of expected pound, floxuridine diacetate (FUDRA)，agic resonance. The stability of FUDRA in mouse serum and tissue homogenates and octanolbuffer partition coeffient of FUDRA ance liquid chromatography (RPHPLC). FUDRA embrane technique. Transmission electron mi