创伤病人救治中的容量复苏(国外英语资料).docVIP

创伤病人救治中的容量复苏(国外英语资料) Recovery of capacity in trauma patients 2003-06-15 14:20:32, liu shinjuku, the third military medical university Acute loss of blood causes hemorrhagic shock to be common in acute trauma. Healthy adults have a blood volume of 4500ml (about 70-80ml/kg), and 30% (1350m1) of blood loss can be life-threatening. The main cause of death in trauma patients is bleeding, which is not actively treated in a short period of time and most patients will die. Timely expansion of plasma capacity and recovery of effective circulating blood capacity are the primary tasks of recovery. Section 1 pathological physiological changes caused by acute blood loss A change in the blood flow of the organ Blood volume fell sharply, first of all, to stimulate the aortic arch and carotid sinus pressure sensors, the nerve center and autonomic nerve is the nerve impulse stimulation can lead to all kinds of hormone release, 5 - HT in the blood, the adrenal cortical hormone and pituitary hormone significantly increased rapidly, strong selectivity of small artery contraction to maintain venous pressure and arterial pressure, peripheral resistance increased obviously, blood redistribution in place to ensure that important viscera perfusion of life. Changes in renal blood flow and glomerular filtration rate When blood pressure was moderate, the renal blood flow and glomerular filtration rate remained normal due to the antipathy of the microarterial. Blood pressure drop to below 8 kpa, increased renal vascular resistance due to decompensation, renal blood flow and glomerular filtration rate decreased, at the same time because of antidiuretic hormone and aldosterone renin - vasopressin - active role has dramatically increase of sodium and water retention. Third, the bodys compensatory condition When acute blood loss is less than 20 percent of normal blood volume, tissue fluid can be taken into the blood vessel from the tissue clearance to replenish blood capacity. Blood loss more than