ICP-MS法测定蛹虫草菌丝体干粉中12种金属元素.pdfVIP

2016 年5 月 中成药 May 2016 Chinese Traditional Patent Medicine Vol. 38 No. 5 第 38 卷第5 期 ICP-MS 法测定蜗虫草菌丝体干粉中 12 种金属元素 王 晶 l ， 黄伟雄l ， 梁晓艳2 ， 胡军高1 ， 梁旭霞1 * (1.广东省疾病预防控制中心，广东广州 511430; 2. 广西中医药大学附属瑞康医院，广西南宁 530011) 摘要:目的 建立电感桐合等离子体质谱 (ICP-MS) 法测定蜗虫草 Cordyceps militaris 菌丝体干粉中铭 (Cr) 、锺 (Mn) 、铁(Fe) 、镇(Ni) 、铜(Cu) 、停(Zn) 、呻(As) 、银(Ag) 、捅(Cd) 、锦(Sb) 、顿(ßa) 、铅(Pb) 的 含有量。方法 湿法消解处理样品后， ICP-MS 法测定其中 12 种金属元素的含有量。结果 口种金属元素的检出限较 低，相关系数均 0.9992。经冻干棒木叶粉和茶叶验证，该方法准确度和精密度良好。结论 蜗虫草菌丝体干粉中 的金属元素均符合相关国家标准。 关键词:蜗虫草菌丝体;于粉;金属元素; ICP-MS 中图分类号: R284. 1 文献标志码:A 文章编号: 1ω1-1528 (2016 )05-1083()5 doi: lO. 3969/j. issn. 1ω1-1528.2016.05.025 Determination of twelve metal elements in dry powder of Cordyceps miUωris my- celium by ICP-MS 1 1 2 1 WANG Jing , HUANG Wei-xiong , LIANG Xiao-yan , HU Jun-gao , LIANG Xu叹ial* (1. Guangdong Provi町归1 Centerfor Di.sea.se Prevention αnd Control , Guangzhou 511430 , Chi阳; 2. Ruikang Hospital j盼liated to Guangxi University of Chinese Medici时• Nanning 530011. Chi阳) ABSTRACT: AIM To establish an inductively coupled plasma-mass spectrometη(ICP-MS) method for determ- ing the contents of Cr , Mn , Fe , Ni , Cu , Zn , As , Ag , Cd , Sb , Ba and Pb in dry powder of Cordyceps militαns mycelium. 岛fETHODS After the samples were treated with wet digestion , the contents of twelve metal elements were determined by ICP-MS. RESULTS The detection limits of twelve metal elements were low , whose correla- tive coefficients were all more than O. 999 2. The method validation was performed on frozen-beech leaf powder and tea leaves with good accuracy and precision. CONCLUSION All the metal elements in dηpowder of Cordycep