大肠癌高发区居民结肠癌危险因素研究_汪祥辉.pdf

# 480 # 2001 11 23 6 Chin J Oncol, Nov mb r 2001, Vol 23, No. 6 ## 汪祥辉 雷通海 马新源 吕桂泉 何兆毅 姚开颜 李其龙 陈康 = , , 109 ( 1B7) , Logistic 10 ( OR = 1. 608) 10 ( OR = 1. 391) ( OR = 9. 887) ( OR = 1. 723) ( OR = 4. 163) ( OR = 3. 421) ; 10 ( OR = 0. 422) = / ; / ; ; Colon cancer risk factors in Jiashan county, Zhejiang province, the highest incidence area in China WANG X ianghui , LEI Tonghai , MA X inyuan, et a 1. Zhej iang Cancer Institute, H ang hou 310022, China = Abstract Objective To inv stigat th risk factors of colon canc r in th high st incid nc ar a, Jiashan county, providing sci ntific basis for monitoring and pr v ntion. Methods With a population-bas d cas- control study, 109 colon canc r pati nts with 1B7 match d controls w r int rvi w d with uniform qu stionnair s. Conditional logistic r gr ssion was us d for univariat and multivariat analysis of colon canc r. Results T n y ars b for , high monthly pork consumption ( OR = 1. 608) , high monthly animal oil consumption ( OR = 1. 391) , psychological d pr ssion ( OR = 9. 887) , n gativ motion ( OR = 1. 723) , low r dig stiv tract dis as s ( OR = 4. 163) , and history of color ctal canc r in th first d gr r lativ s ( OR = 3. 421) w r th main risk factors of colon canc r. At that tim , high monthly v g tabl consumption was a prot ctiv factor for colon canc r ( OR = 0. 422) . Conclusion Colon canc r in Jiashan county was r lat d to di tary factors. Th r s arch r sults support th colon canc r tiological hypoth sis of / fat-bil acid0 and / d fici ncy of di tary fibr s0 . Psychological d pr ssion, inh ritanc and low r dig stiv tract dis as s w r also corr lat d with colon canc r. = Subject words Color ctal n oplasms/ pid miology; Colonic n oplasms/ pid