review of gene expression analysis - 高通量数据 .pptVIP

Analysis of High-throughput Gene Expression Profiling Why to Measure Gene Expression 1. Determines which genes are induced/repressed in response to a developmental phase or to an environmental change. 2. Sets of genes whose expression rises and falls under the same condition are likely to have a related function. 3. Features such as a common regulatory motif can be detected within co-expressed genes. 4. A pattern of gene expression may be used as an indicator of abnormal cellular regulation. ? A useful tool for cancer diagnosis Transitional vs. High-throughput Approaches Techniques Used to Det