核医学-心血管系统（国外英文资料）.docVIP

核医学-心血管系统 Myocardial imaging * myocardial perfusion imaging (a) the principle: normal or functional cardiomyocytes can be selective uptake of certain drug intake and imaging, the location of coronary artery perfusion blood flow is proportional to the local myocardial cell function or activity are closely related. Normal or functional myocardial development, and necrosis and ischemia of the myocardium do not develop (defect) or image thinning (sparse), so as to understand the myocardial blood supply and diagnosis of myocardial disease purposes. 1. Imaging agents: positron drugs, 201TI, 99 MTc labeled compound. Characteristic： The rate of myocardial tissue uptake was high for the first time Distribution and concentration stability during image acquisition Not affected by other drugs Comparison of commonly used myocardial imaging agents: 201TI Advantages: ease of use, temporary marking, completion of load and silent imaging with one shot, and detection of viable myocardium. Disadvantages: the price is too expensive; the half life is long; the image quality is poor. II. 99mTc-MIBI: Advantages: price advantage, short half-life, good image quality, first pass and gated myocardial imaging Disadvantages: load and rest need two times; drug should be marked temporarily. Positron: Advantages: the half-life is short, short-term can be repeated; absolute quantification can be made; myocardial blood flow reserve can be calculated Disadvantages: expensive; PET 2 、 imaging method: 201TI load redistribution imaging 99mTc-MIBI load rest day after day method 99mTc-MIBI load rest day method Dual element method 3, normal image: In general, the left ventricular image is clearly visible. The right ventricle is thin and undeveloped or indistinct. Planar imaging: Body position: ANT, LAO45 degrees LAO70 degrees Count: 500K Matrix: 128 * 128 Magnification: 2 times Tomographic imaging: the distribution of radioactivity in each wall of left ventricle is uniform (1) short axis image: a ring, cen