肝癌无水乙醇灭活后瘤区注射高聚生前后免疫应答的研究.PDFVIP

1·96 · 中国介入影像与治疗学 2007 年第 4 卷第 3 期 　Chin J Int erv Imaging Ther ,2007 ,Vol 4 ,No 3 Study of regional cell immune response on ultrasound guided superantigen injection with anhydrous ethanol injection therapy f or hepatocellular carcinoma Z H E N G M ubai , WA N G J unl i ng , L I X i uy i ng , PA N Quan , CA O A imei ( ) D ez hou Peop les H osp i t al i n S han dong P rov i nce , D ez hou 2530 14 , Chi na ABSTRACT 　Objective 　To st udy t he local immune respon se of inj ecting highly agglutinative st ap hylococci ( HA S) as su p erantigen into t he t umor areas of liver cancer p atient s combing wit h p ercut aneou s anhydrou s et hanol inj ection t herap y ( P EIT) under ult rasound guided . Methods 　All t he 46 ca ses of liver cancer p atient s who were app roved by p at holo gy were t reat ed by P EIT. Then t he p atient s were given inj ection of HA S 1600 unit s into t he local t umor areas in t he t hir d , fort h and sevent h week . The p atient s were given p ercut aneou s biop sy about hep atic inactive focu s under ult rasound guided before p ercut aneou s HA S inj ection . Therap y ( P H IT) and one week lat er . All t he samples were st ained by H E and immunohi sto chemical met ho ds. The infilt ration of CD3 + 、CD4 + 、CD8 + 、CD57 + and CD68 + of local t reat ment area s were comp ared be ( ) + + + fore and aft er P H IT . Results 　 1 Aft er local inj ection of HA S , t he degree of infilt ration of CD