《药理学笔记》(应试版)配套（The pharmacological notes (application version)）.docVIP

《药理学笔记》(应试版)配套（The pharmacological notes (application version)） Pharmacological note Efferent nervous system pharmacology 1. Anatomy knowledge: the delivery of neurotransmitters is classified as follows: 1. Epinephrine nerve: sympathetic nerve 2. Cholinergic nerves: parasympathetic and somatic motor nerves 2. Distribution and effect of efferent nerve control effector and receptor 1. Adrenalin can excite the nerve: it ACTS on the B1 receptor of the heart, which causes the heart rate to be faster, the conduction speed, and the contraction enhancement. A receptor that ACTS on the mucous membrane of the skin and the internal organs of the abdominal cavity, causing it to contract; The B2 receptor that ACTS on the bronchosmooth machine makes it diastolic. The effect is in the eye pupil sphincter a receptor, which causes it to contract 2, cholinergic nerve excitement: role in bronchial smooth muscle, gastrointestinal smooth muscle, pupillary sphincter, ciliary muscle of M receptor, make its shrinkage: role in skeletal muscle of N2 receptors, make it shrink Quasi choline medicine 1, the direct effects on choline receptor choline medicine, direct M excited choline receptor quasi choline medicine: jaborandi alkali, high selectivity of the product in the eyes smooth muscle, thus causing shrinkage, reduce intraocular pressure, adjust the pupil convulsion, clinical effect in ophthalmology, glaucoma, iridocyclitis) 2. Anticholinesterase drugs of easy to reverse: the Ming of nova (1) action mechanism: the reversibility of this product inhibits the activity of cholinesterase and shows the role of pseudocholinergic acid (2) functional use: excited skeletal muscle, treatment of myasthenia gravis: excitatory gastrointestinal and bladder smooth muscle therapy postoperative abdominal bloating and urinary retention 3. Poisoning and rescue of organophosphate Organic phosphate ester (1) poisoning mechanism: refers to the pesticide, it is combined with cholinesterase into hard to hydrolysis