中药分期疗法配合克罗米芬治疗肾虚血瘀型多囊卵巢综合征的临床探究.pdfVIP

提 要 目的: 观察中药分期疗法配合克罗米芬治疗肾虚血瘀型多囊卵巢综合征（PCOS ） 的临床疗效，并初步探讨其作用机理。 方法: 选择 60 例确诊为多囊卵巢综合征，中医辨证为肾虚血瘀型的患者，采用 随机对照试验方法，分为治疗组、对照组。治疗组(30 例)给予中药分期疗法配合克 罗米芬治疗，对照组(30 例)给予西药克罗米芬治疗，共治疗三个月经周期。观察治 疗前后患者中医临床症候改善情况，妊娠情况，宫颈评分变化情况，基础体温(BBT) 以及促卵泡激素(FSH)、黄体生成素(LH)、睾酮(T)值等。 结果: 使用中西医结合疗法在综合疗效比较、中医临床症候改善、妊娠情况、治 疗前后宫颈评分比较优于单纯西药疗法；两组在排卵率比较差异无显著性 （P0.05）； 治疗后，两组均可降低 PCOS 患者血清 LH 、LH/FSH 值，两组间在治疗后血清 FSH 、 LH 、LH/FSH 值比较，差异亦有统计学意义(P0.05)。 结论：中药分期疗法配合克罗米芬治疗肾虚血瘀型PCOS ，能有效改善月经及临 床症状，能明显降低患者 LH 、T、LH/FSH 值，提高排卵,改善内分泌环境，提高妊 娠情况。 关键词 多囊卵巢综合征；中药分期疗法；肾虚血瘀；克罗米芬 Clinical Research on Treating Kidney Deficiency and Blood Stasis Type Polycystic Ovarian Syndrome with Chinese Medicine Installments Therapy and Clomiphene Citrate Speciality :Gynecology of TCM Author:Hao Jianjun Tutor :Professor Liu Jingjun Abstract Objective: Observe the effect of Chinese medicine installments therapy with Clomiphene citrate treatment of kidney blood stasis Polycystic Ovarian Syndrome (PCOS) clinical efficacy and to explore its mechanism. Methods: 60 patients diagnosed with PCOS, TCM kidney deficiency and blood stasis type of patients , the use of randomized controlled trials , divided into treatment group and control group . The treatment group ( 30 cases ) given Chinese Medicine Installments Therapy with clomiphene citrate therapy, the control group ( 30 cases ) to give western medicine clomiphene citrate, were treated for three menstrual cycles . Before and after treatment , clinical symptoms of patients with traditional Chinese medicine to improve the situation, circumstances of pregnancy , cervical score changes , basal body temperature (BBT) and follicle-stimulating hormo