健脾疏肝汤治疗肝郁脾虚型功能性消化不良的临床探究.pdfVIP

提 要 目的：观察健脾疏肝汤治疗功能性消化不良（Functional Dyspepsia ，FD），中 医辩证为肝郁脾虚型的功能性消化不良临床疗效，并从理论和临床研究两个方面探讨 健脾疏肝汤治疗功能性消化不良的机制。方法：临床选择符合纳入标准的功能性消化 不良患者63例，随机分为两组，治疗组（32例）给予健脾疏肝汤水煎剂，对照组（31 例）给予逍遥丸，观察两组的临床疗效。结果：临床研究显示，治疗组治愈9例，显 效 17 例，有效 3 例，愈显率（痊愈+显效率）为 81.25％，总有效率为 90.63％。对 照组临床痊愈 4 例，显效 6 例，有效 11 例，愈显率为 32.26％，总有效率为 67.74 ％。治疗组显著优于对照组（愈显率比较P0.01，总有效率比较P0.05）。治疗组在 中医证侯总积分和消除或改善胃脘胀满或疼痛，食少纳呆，便溏不爽等症状上，疗效 优于对照组。结论：健脾疏肝汤是治疗肝郁脾虚型功能性消化不良的有效方剂，其机 理可能与调节胃肠运动，降低内脏高敏感性，以及对胃肠肽及免疫的调节等有关。 关键词 健脾疏肝汤；功能性消化不良（Functional Dyspepsia ,FD）；肝郁脾 虚型；临床研究 Clinical research on the treatment of Functional dyspepsia (FD) caused by liver-depression and spleen deficiency Speciality： internal medicine of TCM Auther ： Li Yan Yun Tutor ： Lu Guang Chao Abstract Objectives：To observe the clinical effects in treating Functional Dyspepsia (FD) caused by liver-depression and spleen deficiency.with Jian Pi Shu Gan Tang to analyze the mechanism of this therapy in treating FD . Methods ：This research was based on 63 cases of outpatients with liver-depression and spleen deficiency from the clinic of the hospital attributed to TCM of shan dong province.They were randomly divided into two groups. One group was the treatment group,the patients of which were treated with Jian Pi Shu Gan Tang.The other group was the control group ，with patients being treated with Xiao Yao Wan. Treatement group were made up of 32 cases and another were made up of 31 cases. These patients all met the TCM diagnosis criterion. Results ：After one course of treatment,significant difference was apparent in the clinical effects:In the treatment group,9 cases recovered and 17 cases significantly improved,(thus the effectual ra