加味生脉饮影响颈动脉粥样硬化的临床探究.pdfVIP

提 要 目的：通过观察患者的临床症状、体征及颈总动脉内膜中层厚度（IMT）来探讨 加味生脉饮的抗动脉粥样硬化作用机制及其临床疗效。 方法：将 60 名患者，随机分成两组，治疗组 30 例，对照组 30 例。对照组常规 选用药物（高血压患者根据病情合理选择服用降压药；冠心病患者可服用硝酸异山梨 酯等药物；高脂血症病人给予合理的控制血脂的药物；糖尿病患者予以控制血糖的药 物；脑梗塞患者根据病情予以合理临床治疗药物）口服治疗；治疗组在常规药物治疗 的基础上加服加味生脉饮，治疗周期为 6 个月。观察治疗前后患者临床症状、体征和 颈总动脉内中膜厚度(IMT)指标的变化。 结果：临床观察６个月，治疗组中医证候积分及日常生活能力状态评分均得到改 善，且两组间比较有明显差异（P0.05 ），治疗组明显优于对照组。颈总动脉内中膜 厚度（IMT ）比较，两组间比较无明显差异（P0.05 ）。治疗组临床功能总有效率为 90.00%，明显优于对照组的 80.00%。 结论：加味生脉饮有抗动脉粥样硬化的作用。可能与加味生脉饮具有调节血脂， 改善内皮功能，调节血管张力，缓解血管痉挛等作用有关。 关键词 加味生脉饮；动脉粥样硬化；颈总动脉内中膜厚度；益气养阴 “Modified Shengmaiyin”afffect carotid atherosclerosis in clinical research Speciality: Internal Medicine of TCM Tutor: prof.LiRui Author:zhaibing Abstract Objective：Through the use of Modified ShengmaiYin carotid athero- sclerosis and clinical study of the theory to explain the medical effects of atherosclerosis in the clinical features, proposed Modified huangqi ShengmaiYin treat atherosclerosis, improve clinical Symptoms, to alleviate the suffering of patients. Methods ：60 cases were divided into two groups at random：the treatment group of “Modified shengmaiyin”and routine western medicine and the control group of routine western medicine (Reasonable choice according to the disease in patients with hypertension taking antihypertensive drugs; coronary heart disease patients can still take isosorbide esters and other drugs; hyperlipidemic patients given a reasonable control of lipid drugs; diabetes drugs to control blood sugar; infarction patients according to Clinical treatment condition to be reasonable). ， The treatment cycle is 6 months. Changes of clinical symptoms signs and lab indexes were detected be