加味茵陈蒿汤保留灌肠对慢性重型肝炎患者内毒素及血氨的影响.pdfVIP

提 要 目的：观察加味茵陈蒿汤保留灌肠对慢性重型肝炎患者内毒素和血氨的影响，评 价中药复方保留灌肠治疗慢性重型肝炎疗效。 方法：临床选择纳入标准的湿热瘀毒型慢性重型肝炎60例，随机分为治疗组和 对照组各30例，对照组在综合治疗的基础上给予乳果糖30ml po tid，治疗组在综 合治疗的基础上给予加味茵陈蒿汤保留灌肠。比较两组的临床疗效。 结果：研究结果显示，两组治疗后都能明显改善肝功能、降低并发症发生率。治 疗组在改善临床症状及ALT、AST、TBIL、ALB、PTA方面优于对照组（P0.01或P0.05）； 在降低内毒素和血氨的含量方面，其疗效明显优于对照组（P0.01或P0.05）。 结论：加味茵陈蒿汤保留灌肠能有效改善慢性重型肝炎的临床症状，改善肝功能， 降低内毒素和血氨的含量，在临床应用中安全、有效。 关键词 加味茵陈蒿汤；保留灌肠；慢性重型肝炎；内毒素；血氨 Modified Yinchenhao of Chronic Severe Hepatitis Effects of Endotoxin and Ammonia, and To Explore Its Mechanism Specialty：Internal Medicine of TCM Author ：Qin Shuxia Author ：Professor Sun Jianguang Abstract Objective: To observe the the flavored Yinchenhao soup retention enema of endotoxin and ammonia in patients with chronic severe hepatitis, and to explore its mechanism. Methods: The clinical select the criteria for inclusion of damp heat and toxic chronic severe hepatitis 60 cases were randomly divided into treatment group and control group 30 cases, the control group on the basis of the comprehensive treatment given lactulose 30ml po tid treatment group in the comprehensive treatment the basis give flavored Yinchenhao in soup retention enema. Clinical efficacy of the two groups were compared. Results: The results showed that the two groups after treatment can significantly improve liver function, reduce the incidence of complications. Treatment group than the control group (P 0.01 or P 0.05) in improvement of clinical symptoms and ALT and AST, TBIL, ALB,PTA; in reducing the content of endotoxin and ammonia, were significantly better than the control group (P 0.01 or P 0.05). Conclusion: Modified Yinchenhao, Decoction enema can effectively improve the cl