加味生脉散治疗老年慢性心力衰竭（气阴两虚型）的疗效视察.pdfVIP

提 要 目的：观察加味生脉散治疗老年慢性心力衰竭（气阴两虚型）的临床疗效，并探 究其治疗优势。 方法：将 60 例符合纳入标准的患者随机分为试验组和对照组，每组 30 人。对照 组采用西医常规治疗，试验组在对照组基础上加用加味生脉散；治疗周期为 4 周。观 察治疗前后患者心功能分级、脑钠尿肽（BNP ）、生活质量及中医证侯评分改善情况。 结果：两组在心功能分级、BNP 治疗前后的比较中均有良好的改善作用 （P=0.0000.01) ，组间疗效无统计学差异（心功能分级 P=1.0000.05 ，BNP P=0.5480.05 ）。中医证侯评分比较中试验组显效率 43.3% 、有效率 53.3%、总有效 率为 96.7%，与对照组比较有显著差异(P=0.0000.01) 。生活质量方面两组治疗前后 组内比较体力、社会关系、情绪影响及总分均有显著改善(P=0.0000.01) ；试验组各 项改善程度均优于对照组(P=0.0000.01) 。 结论：加味生脉散通过益气养阴，补益心脾提高心功能，改善老年慢性心力衰竭 患者的临床症状及心理状态，提高生活质量，是临床治疗老年慢性心力衰竭（气阴两 虚型）的有效方剂，值得临床广泛应用。 关键词 加味生脉散；老年慢性心力衰竭；气阴两虚型；临床研究 CLINICAL OBSERVATION OF CURATIVE EFFECT OF JIAWEISHENGMAI DECOCTION ON THE AGED CHRONIC HEART FAILURE (QIYIN DEFICIENCY) Speciality: Internal Medicine of TCM Author:ZHANG Yanhong Tutor:CHEN Zetao Abstract Purpose: To observe the clinical curative effect of Jiaweishengmai decoction on the aged chronic heart failure (qiyin deficiency) and investigate its curative preponderance. Method: 60 patients were selected according to the diagnostic criteria and randomly divided into two groups, 30 as the experimental group and the other 30 as the control group. Both groups were treated by western medical regular therapy, while the Jiaweishengmai decoction was applied to the experimental group in addition. The treatment cycles for the two groups were both 4 weeks. The improvement statements of main clinical syndrome (cardiac functional grading), quality of life, and traditional Chinese medicine (TCM) disease score and the changes of brain natriuretic factor (BNP) were observed before and after the treatment. Result: Both groups have good improvements in cardiac functional grading and BNP after the treatment (P=0.0000.01). There are no differences in the curative effect between the groups